INTRODUCTION: Brief commentary on the topic leading to the thesis statement. There is a connection between creativity and madness and the association arises from the need for an unconventional thought process to spark creativity and the biological factors surrounding madness. brains of creative individuals and mentally ill patients. Would this be madness? There is a correlation between a more creative individual and a mentally ill patient, and it is very likely that the former could be the latter. The question of whether high mental abilities, whether creativity in professions such as the arts or literature, or high intellectual skills in engineering or science, are linked to madness and melancholy has always been a controversy; a cultural notion that has been constantly debated. This relationship has been discussed from the beginning of Greek civilization where even in prehistoric Greek myths, a relationship between madness and creativity is presented in the mythical gods of the Olympians. Dionysian [the son of Zeus], ​​as noted by Kay Redfield Jamison (1996), a noted psychologist with intriguing results in her research linking creativity to mental disorders, is one of the first cases to examine when we compare melancholy to creativity. Dionysian was pure genius in his creation and art, as Jamison notes, but he was also known for his excessive use of force and aggression towards his people to the point that he was considered mad; it became not only a symbol of creativity, but it also symbolized madness. Additionally, the connection between madness and talent was also highlighted by the great Greek philosopher Plato, who believed that poets were driven by a touch of madness, as highlighted by (Gayford, 2007). Aristotle, a Greek ...... middle of paper ...... mentally ill, will have a close relative who suffers from a mental disorder. Furthermore, he adds by noting that famous scientists and creative individuals such as Einstein, Sir Isaac Newton and Bertrand Russell are all said to have parents with schizophrenia and mental illnesses. Additionally, the argument that genes are behind this relationship has become more compelling, as shown by recent studies of neuregulin 1, a gene that plays a major role in improving communication ability. between neurons in the brain, which, in turn, strengthens The brain's ability to understand has been shown to be the missing link between mental disorders and creativity (Isanski, 2009). Not only does it improve the brain's ability to understand, but it also increases the chances of an individual developing psychotic illnesses such as bipolar disorder and schizophrenia..