Understanding the Syndrome, Complications and Nursing ConsiderationsIntroductionMild muscle pain can be a common side effect of physical means, such as intense workouts, overuse of muscles and/ or blocked blood vessels. , or by chemical means, such as toxins, heat or drugs. Often, people who suffer from muscle pain can easily identify the cause through their knowledge of the stress, tension or physical activity they have endured. Rhabdomyolysis, or skeletal muscle dissolution, is a syndrome caused by skeletal muscle injury and involves the leakage of large amounts of potentially toxic intracellular contents into plasma (Muscal, 2013). Unlike mild muscle pain, rhabdomyolysis, commonly referred to as “Rhabdo,” can lead to life-threatening kidney failure and disseminated intravascular coagulation (DIC), while also being multifactorial in adult patients (Muscal, 2013). Approximately 28-37% of all cases of rhabdomyolysis in the United States require short-term hemodialysis (Melli G, 2013). The purpose of this article is to explore the causes, signs and symptoms, nursing considerations, and training trends that are blamed for inducing “Rhabdo” in athletes. in the United States every year (Melli G, 2013). Sixty percent of these cases in adults include multiple factors such as trauma and compression leading to direct muscle damage, vessel occlusion due to thromboembolism or surgical clamping, prolonged immobilization, burns and fractures. . However, rhabdomyolysis in pediatric patients is often caused by infections, trauma, metabolic disorders, and muscle diseases. (Mannix R,...... middle of article ......ry and rhabdomyolysis. Crit Care Clin. Jan 2004;20(1):171-92.Mannix R, Tan ML, Wright R, Baskin M. Acute pediatric rhabdomyolysis: causes and rates of renal failure Pediatrics 118(5): 2119-25Melli G, Chaudhry V, Cornblath Rhabdomyolysis: an evaluation of 475 hospitalized patients. , E. (September 16, 2013). Retrieved from Medscape: http://emedicine.medscape.com/article/1007814-overview.Ray, M. (January 2010). The truth about rhabdomyolysis. Retrieved from CrossFit Journal: http://journal.crossfit.com/2010/01/rhabdo-pdf.tpl#featureArticleTitleSauret, JM (March 1, 2002). : http://www.aafp.org/afp/2002/0301/p907.htmlVanholder R, Sever MS, Erek E, Lameire N. Rhabdomyolysis J Am Soc Nephrol Aug. 2000;11(8):1553-61.