IntroductionDrug use among high school students is not something that just happened with the legalization of marijuana or with the endless legal supply of prescribed amphetamines to anyone who claims to be unable to concentrate. Although drug use has become somewhat normalized in our society - whether experimental use, recreational drug use, or habitual marijuana use - this does not mean that the risk of Normal drug use can quickly turn into drug addiction or even dependence. chooses to use drugs and is exposed to some risk, including overdose and death. Is there a gene or trait that may make some people more likely to abuse or become dependent on drugs than others? This article seeks to explore the correlation between levels of self-esteem among high school girls and drug use. Specifically, it seeks to find out what the majority of students at a specific high school consider normal drug use as a control variable. After obtaining the control variable, girls in each grade level of that same high school will receive a series of two surveys: one used to measure the level of self-esteem and one regarding drug use which is identical to the one used for establish control. These surveys will be pre-marked with matching ID numbers so that they can be traceable to each other while maintaining subject anonymity. Literature Review Drug use among young men and women aged 12 to 19 Drug use among adolescents and young adults has become quite widespread over the past 25 years, with many calling this increase proportions epidemics. There has been countless research devoted to understanding why drug use often begins during adolescence...... middle of article ......., & Gordon-Larsen, PhD, P. (2010). Perception of overweight and self-esteem during adolescence. International Journal of Eating Disorders, 447-54.Semple, PhD, SJ, Grant, MD, I., & Patterson, PhD, TL (2004). Methamphetamine users: social characteristics and sexual risk behaviors. Women and health, 35-50. Stewart, SH, Conrad, PJ, Pihl, RO and Dongier, M. (1999). Relationships between dimensions of posttraumatic stress symptoms and substance dependence in a community-recruited sample of substance abusing women. 13(2), 78-88. Venturelli, P. J. (2000). Drugs at school: myths versus facts. Annals of the American Academy of Political and Social Science, 567, 72-87. Willis, T. A. (1994). Self-esteem and perceived control in adolescent substance use: Comparative tests in concurrent and prospective analyses. Psychology of addictive behaviors, 8(4), 223-34.