Table of ContentsHuntington's DiseaseDisorder ScreeningConclusionDiseases caused by dynamic mutations involve an unstable causative mutation. Such disorders are characterized by uncontrolled expansion of part of the DNA inside the diseased gene, consisting of repeated units of three or more tandem nucleotides. Generally, there are polymorphic alleles in genes associated with these diseases. Say no to plagiarism. Get a tailor-made essay on “Why Violent Video Games Should Not Be Banned”? Get the original essayHuntington's DiseaseThis disease is acquired in an autosomal dominant pattern. Huntington's disease is a dynamic brain problem that causes uncontrolled development, intense topics, and loss of thinking (perception) ability. The most widely recognized type of this problem, adult onset Huntington's disease, usually occurs around age 30 or 40. Early signs and side effects may include grumpiness, melancholy, minor automatic developments, poor coordination, and problems adapting to new data or basic leadership. Many people experience ongoing developments of pulling or jerking known as chorea with Huntington's disease. Such movements become increasingly articulated as the disease progresses. Influenced people may have difficulty walking, speaking, and swallowing. Huntington's disease is caused by changes in the HTT gene. The HTT gene indicates the best way to make a protein called huntingtin. Although the actual capacity of this protein is vague, it appears to play an important role in nerve cells (neurons) in the brain. The HTT change causing Huntington's disease includes a DNA fragment known as the CAG trinucleotide repeat. This segment includes a progression of three squares of DNA structure (cytosine, adenine and guanine) which appear successively several times. The CAG area is usually mimicked within the gene 10 to several times. Predictive Disorder Screening - Predictive screening for genetic mutations that trigger Huntington's disease allows people who know they are at risk to know if they will develop HD in the future. For multiple therapy appointments, people who want predictive tests generally have to go in person to a specialized clinic. Prenatal – Expecting parents seek prenatal testing when a parent is diagnosed with or carries the gene for Huntington's disease. Prenatal tests will show whether the defective gene is inherited by the infant. ... If the fetus tests positive, the parents will determine whether to terminate the pregnancy. Theory behind the tests - The discovery of the HD gene contributed to a genetic test for the diagnosis or confirmation of Huntington's disease. Using a blood sample, counting the number of CAG repeats in the huntingtin genome, the genetic test analyzes the DNA for the HD mutation. Individuals without HD typically have 28 repeats or fewer.Keep in mind: This is just a sample.Get a personalized article now from our expert writers.Get a custom essayConlcusionHuntington's disease is caused by a mutation gene dynamics. Interestingly, Adolf Hitler suffered from this disease. It is not a common disease and therefore little studied; research into its treatment and prevention is still ongoing.