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  • Essay / Hepatitis B virus (HBV) - 622

    Hepatitis B virus (HBV) is a serious and common virus that has infected "more than two billion people alive today at one time their lives.”1 It is a hepadanavirus that interferes with liver functions because it replicates in hepatocytes (liver cells) and induces an immune response responsible for liver inflammation.2 Viruses are not mobile , meaning that HBV is also sessile and does not form spores. The spherical virion, called the Dane particle3, is 42 nm in diameter and binds to the surface of the hepatocyte.1 The virion itself contains a 27 nm thick inner protein core filled with circular, partially double-stranded DNA , DNA polymerase and reverse transcriptase.1 It is an enveloped virus, so it also contains an outer lipoprotein envelope4 that is 7 nm thick and composed of many integrated surface proteins such as surface antigen for binding and entry of the virus.1 HBV has an average incubation period of three months, meaning that it does not begin to show symptoms during the first three months that the person is infected and that person can unknowingly infect other people.2 ...