IntroductionTyphoid fever is a potentially fatal illness caused by the bacteria Salmonella Typhi. Worldwide, typhoid fever affects approximately 17 million people each year, causing nearly 600,000 deaths. The causative agent, Salmonella enterica typhi (now called Salmonella typhi), is an obligate parasite that has no known natural reservoir other than humans. Little is known about the historical emergence of human S. typhi infections, but it is believed to have caused the deaths of many figures such as British author and poet Rudyard Kipling, the inventor of the airplane, Wilbur Wright and Alexander of the Greek Empire. the Great. The first recorded outbreak occurred in Jamestown, Virginia, where an estimated 6,000 people died of typhoid fever in the early 17th century. This disease is rare in the United States and developed countries, but still poses a risk of emergence. Originally isolated in 1880 by Karl J. Erberth, S. typhi is a multi-organ pathogen that inhabits the lymphatic tissues of the small intestine, liver, spleen, and bloodstream of infected humans. It is not known to infect animals and is more common in developing countries with poor sanitation systems and a lack of antibiotics, putting travelers to Asia, Latin America and Africa in a high-risk group. Of the 266 people infected in the United States in 2002, approximately 70% had traveled abroad within 6 weeks of illness onset. Spread of typhoid fever Salmonella Typhi only lives in humans. People with typhoid fever carry the bacteria in their blood and intestinal tract. Additionally, some people, called carriers, recover from typhoid fever but still carry the bacteria. Sick and carrier people shed Salmonella Typhi in the middle of the paper group ......atment. Bacteremia was established in the treatment groups. The white blood cell (WBC) count in rabbits infected with Salmonella typhi but later kept on ogi decreased from 4,900 mm³ to 4,200 mm³. Similarly, leukocyte counts decreased from 7,300 mm³ to 6,300 mm³ in rabbits initially infected (but fed a commercial diet) and then fed ogi. It could be concluded that ogi could be effective in preventing Salmonella infection and reducing the microbial load of Salmonella typhi in the blood of mammals, as shown by microbial and hematological indices. ConclusionIn conclusion, typhoid fever can be treated with antibiotics. However, resistance to common antimicrobials is widespread. Healthy carriers should be excluded from handling food. Unfortunately, we have more salmonella today than in the past because more and more chickens are sick..